We have developed the CompMut-TB framework which can assist with identifying compensatory mutations which is important for more precise genome-based profiling of drug-resistant TB strains and to further understanding of the evolutionary mechanisms that underpin drug-resistance.
Work from a joint project with the Thailand MOPH has been published. It demonstrates the usefulness of whole genome sequencing for clinical and surveillance applications
Nina Billows 
Joseph Thorpe 
Matt Higgins